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logo of cancer IV-(b). Theoretical Analysis of Signet Ring Cell Adenocarcinoma
Section: b1 | b2 | b3 | b4 | b5 | b6

(5) Outbreak of Signet Ring Cell Adenocarcinoma
(Outbreak of Third Distortion)

When the stomach wall cannot bear the tensile strength of the amplified tissue distortion: secondary distortion, it causes cancer at the peak of the secondary distortion; that is, this cancer occurs in the lamina propria mucosae nearby the mucosal epithelium. In this case, the stomach wall has caused strong secondary distortion, which is in the direction from the mucous epithelium to the lamina propria mucosae. Thus, when the stomach wall cannot bear the tensile strength of the secondary distortion, it disconnects the connection in energy flow between cells in the lamina propria mucosae; then, an invisible hole occurs there. Additionally, even after the stomach wall caused an invisible hole, it is continuously oppressed by the posterior force which has already occurred at the preceding step. Thus, the stomach wall causes, in the invisible hole, new tissue distortion also by raising the momentum. This new tissue distortion, which indicates third distortion, transforms its containing cells into new cells: signet ring cell adenocarcinoma cells. Through this process, the stomach causes signet ring cell adenocarcinoma in the lamina propria mucosae nearby the mucosal epithelium.

Notice that this new distortion, third distortion, is in the same direction as its secondary distortion. Although third distortion at adenocarcinoma is in the opposite direction to its secondary distortion, third distortion at signet ring cell adenocarcinoma is in the same direction as its secondary distortion. This is also one of the important different points between adenocarcinoma and signet ring cell adenocarcinoma.

Fig28. Outbreak of Signet Ring Ad-Ca
(Outbreak of Third Distortion)

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