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logo of cancer IV-(c). Theoretical Analysis of Leiomyosarcoma Arising from Lamina Muscularis Mucosae
Section: c1 | c2 | c3

(2) Amplification of Tissue Distortion
(Outbreak of Secondary Distortion)

When the stomach with initial distortion decreases the momentum, it starts amplifying the initial distortion stepwise. The stomach changes the momentum by using the fractal movement, so that it changes the momentum step by step. Furthermore, an organ with initial distortion amplifies the initial distortion by changing the momentum. Thus, when the stomach already causing initial distortion also decreases the momentum, it starts amplifying the initial distortion step by step. This amplified initial distortion indicates secondary distortion. The figures on the next page show the stepwise change in amplifying tissue distortion.

Importantly, this secondary distortion is in the direction from the submucosa to the lamina muscularis mucosae, and its peak is in the lamina muscularis mucosae. The surface three layers have decreased their metabolic activity, and tend to easily decrease their momenta. In contrast, other layers maintain their normal metabolic activity, and tend to decrease their momenta in parallel to the momentum contained in the stomach wall. Thus, when this stomach wall decreases the momentum, the surface three layers decrease their momenta strongly although other layers decrease their momenta slightly. By this mechanism, this secondary distortion enlarges in the direction from the submucosa to the lamina muscularis mucosae, and its peak is in the lamina muscularis mucosae.

Fig31. Amplification of issue distortion
(Amplification of Secondary distortion)

Points:
Also this stomach wall, of course, amplifies the tissue distortion stepwise because of the fractal structure. This process is quite the same as those at adenocarcinoma and at signet ring cell adenocarcinoma. The figure above clearly shows this process.

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